教师名录
汪海燕，专职副研究员/硕士生导师
主要研究方向：
1.生物芯片制备，包括基于微米和纳米级生物传感界面的新型生物芯片设计、开发、制备和测试。
2.微纳传感，包手微纳流体设计和动力学模型构建。
3.精准诊疗芯片开发，针对“卡脖子”问题，面向临床需求开发快速诊断核心技术。
4. 蛋白质测序技术，包括纳米孔单分子测序技术的开发和控制技术。
科研方面：
近年来发表论文22篇，授权专利1项。包括主要包括Chem. Commun.、Anal. Chem.和ACS Sensor.等 担任Result in Chemistry的专刊编辑和多个学术期刊的审稿专家，包括专业领域一区期刊Chemical Science和ACS Sensors。
2019.12-至今 437必赢会员中心 437必赢会员中心 专职副研究员
2015.02- 2019.10 美国国家标准与技术研究所 Guest Researhcer
Chemical Science
ACS Sensors
Analytical Chemistry
Guest Editor of Results in Chemistry
2013.10 华东理工大学“研究生国家奖学金”
2013.04 华东理工大学“2013年度优秀博士毕业生”
2012.10 华东理工大学“优秀学生干部”
2012.10 华东理工大学“优秀社会工作奖一等奖”
2011.12 华东理工大学“高水平论文奖”
2010.10 华东理工大学计划外奖学金：天鼎东岳一等奖
1. Wang H.-Y.*,Liu Y.*Near Infrared Light-Activatable Platelet-Mimicking NIR-II NONano-Prodrug for Precise Atherosclerosis Theranostics. Adv. Sci., in Proof.
2. Hui Yu, Yun Chai, Aliya Tiemuer,Yuxuan Han, H.-Y. Wang*, Yi Liu*, Frequency upconversion luminescence:New frontiers in bioapplications, Coord. Chem. Rev., 2023, 496, 215379.
3. Zhao C., Zhou F., Lu K. Yang S., TanB., Sun W., Shangguan L., Wang H.-Y.*, Liu Y.*, Near-infraredfluorescent probe for in vivo monitoring acetylcholinesterase activity. Sens.Actuators B: Chem. 2022, 360, 131647.
4. Liu W., Yao X., Zhu W., Wang J.,Zhou F., Qian X., Tiemuer A., Yang S., Wang H.-Y.*, Liu Y., Azo-BasedHypoxia-Responsive Self-Assembly Near-Infrared Fluorescent Nanoprobe for InVivo Real-Time Bioimaging of Tumors. ACS Appl. Bio Mater.2021,4, 3, 2752–2758.
5. Yu H.,Sun W., Tiemuer A., Zhang Y., Wang H.-Y. *, Liu Y.*,Mitochondria targeted near-infrared chemodosimeter for upconversionluminescence bioimaging of hypoxia.Chem. Commun., 2021,57, 5207-5210.
6. Qian X., Zhu W., Yu H., Xu Y., Liu W., Wang H.-Y. *, LiuY.*, Mitochondria-targeted near-infrared fluorescent probe for monitoring of aCopper(I) in living cells and In vivo.Dyes and Pigments, 2021, 194,109561.
7. Zhu W.,Qian X., Wang J., Yu H., Liu W., Wang H.-Y.*, Liu Y.*, Near-infraredfrequency upconversion probes for monitoring glutathione S-transferase toevaluate acute liver injury. Sens. Actuators B: Chem.2021, 347,130640.
8. Zhu W., Yu H., Qian X., Lu K., Zhao C., Zhang Y., Wang H.-Y.*, Liu Y.*, Near-infraredfrequency upconversion probe for revealing the relationship between glutathioneS-transferase and drug-resistance. Anal. Chim. Acta. 2021, 1181, 338920
9. WangH.-Y., Kasianowicz J. J., Robertson, J.W.F., PosterL. D., and Ettedgui, J., A Comparison of Ion Channel Current Blockades Causedby Individual Poly (ethylene glycol) Molecules and PolyoxometalateNanoclusters. The Euro. Phys. J. E.2019,42 (6),83.
10. Wang H.-Y., ZhangH., Chen S., Liu Y.*, Fluorescein-Inspired Near-Infrared Chemodosimeter forLuminescence Bioimaging. Current med. Chem.2019, 26 (21),4029-4041
11. Wang H.-Y., Ettedgui, J., Forstater, J.H.,Robertson, J.W.F., Reiner J. E., Zhang H., Chen S.,Kasianowicz, J.J. Determining the physical properties ofmolecules with nanometer-scale pores. ACSSens.2018, 3, 251-263.
12. Liu Y.,Yao X.-F. & Wang H.-Y.*, ProteinDetection Though Single Molecule Nanopore. Chin.J. Anal. Chem.2018, 46,6, e1838-e1846.
13. Wang, H.-Y.,Song, Z.-Y., Zhang, H.-S., & Chen, S.-P. Single-molecule analysis of lead(II)-binding aptamer conformational changes in an α-hemolysin nanopore, andsensitive detection of lead (II). Microchim.Acta2016, 183,1003-1010.
14. Wang, H.-Y.,Gu, Z., Wang, J., & Long, Y.-T. Analysis of a single α-synucleinfibrillation by the interaction with a protein nanopore. Analy. Chem.2013, 85,8254-8261.
15. Wang, H.-Y.,Li, Y., Qin, L.-X., Heyman, A., Shoseyov, O., Willner, I., Long, Y.-T., &Tian, H. Single-molecule DNA detection using a novel SP1 protein nanopore. Chem. Commun.2013, 49, 1741-1743.
16. Wang, H.-Y.,Ying, Y.-L., Li, Y., Kraatz, H.B., & Long, Y.-T. Nanopore analysis ofβ-amyloid peptide aggregation transition induced by small molecules. Anal. Chem.2011, 83, 1746-1752.
17. Wang, H.-Y.,Ying, Y.-L., Li, Y., & Long, Y.-T. Peering into Biological Nanopore: APractical Technology to Single‐Molecule Analysis. Chem. An Asian J.2011, 5, 952-1961.
18. LiuY., Wang S., Ma Y., J Lin, Wang H.-Y.,Gu Y., Chen X., Huang P. Ratiometric photoacoustic molecular imaging formethylmercury detection in living subjects. AdvancedMater. 2017, 29, 1606129.
19. Kasianowicz,J.J., Balijepalli, A.K., Ettedgui, J., Forstater, J.H., Wang, H.-Y., Zhang, H.,& Robertson, J.W.F. Analyticalapplications for pore-forming proteins. Biochim.Biophy. Acta – Biomembran.2016, 1858, 593-606.
20. Ying,Y.-L., Wang, H.-Y. Sutherland, T.C. & Long, Y.-T. Monitoring of anATP‐Binding Aptamer and its Conformational Changes Using an a-HemolysinNanopore. Small2011, 1, 87-94.
21. Liu,Y., Ying, Y.-L., Wang, H.-Y., Cao, C., Li, D.-W., Zhang,W.-Q., & Long, Y.-T. Real-time monitoring of the oxidative response of amembrane–channel biomimetic system to free radicals. Chem. Commun.2013, 49, 6584-6586.
22. Liu,T., Bao, C., Wang, H.-Y., Lin, Y., Jia, H., & Zhu, L.Light-controlled ion channels formed by amphiphilic small molecules regulateion conduction viacis–transphotoisomerization. Chem. Commun.2013, 49, 10311-10313.
23. 喻皓，汪海燕，龙亿涛等基于LabVIEW的纳米通道单分子检测系统，授权专利号：ZL2010 2 0169643.6
2020.01-2020.12, 项目主持人，中央高校基本业务费基础科研扶持项目-理工类：基于纳米孔的生物仿生界面机械性能研究（2242020K40221）
2014.09-2016.12, 项目主持人, 中国博士后科学基金第56批一等资助项目：纳米通道用于核酸适配体单分子识别行为研究（2014M560670）
2021.01-2024.12 项目参与人，国家自然科学基金面上项目：固态纳米孔核酸检测的关键技术和机理 (52075099)
喻皓，汪海燕，龙亿涛等基于LabVIEW的纳米通道单分子检测系统，授权专利号：ZL 2010 2 0169643.6
